Chief Medical Officer, ClearCardio®

Meet Dr. John Osborne, MD PhD FACC FNLA

The architect behind ClearCardio's “living autopsy” approach to heart and stroke prevention.

Portrait of Dr. John Osborne, Chief Medical Officer of ClearCardio

Three decades on one question

He's not an influencer who read a few studies. He's a Harvard-trained cardiologist, a PhD cardiovascular physiologist, and a fellow of both the American College of Cardiology and the National Lipid Association who has spent three decades doing one thing: figuring out how to see and reverse artery disease before it kills people.

After graduating magna cum laude in medicine and earning a PhD in cardiovascular physiology, Dr. Osborne completed his internal medicine and cardiology training at Brigham and Women's Hospital and Harvard Medical School. He then went deeper, doing post-doctoral work in the molecular genetics of inherited heart disease in one of the world's leading labs.

Early in his career he saw the same pattern over and over: people only “found out” they had heart disease in the cath lab or the ER — when the damage was already done. That pushed him away from a career in mechanical fixes and toward aggressive, data-driven prevention.

A pioneer of non-invasive plaque imaging

He became one of the early pioneers of cardiac CT and non-invasive plaque imaging, leading one of the first freestanding 256-slice CT programs in North America and later overseeing installation of the first 640-slice ATLAS system in the United States.

He has served as Director of Preventive Cardiology and Cardiovascular Imaging in multiple systems, run major clinical trials that changed global cholesterol and diabetes care, and helped shape national guidelines as a trusted voice within the American Heart Association and National Lipid Association.

His mission today

End heart attacks and strokes as we know them — one precisely measured artery at a time.

Where his time goes

  • Reviewing patients' CT and AI analyses
  • Designing and refining the treatment playbooks our physicians use
  • Staying on the bleeding edge of research, so ClearCardio patients get tomorrow's tools today
  • Teaching through podcasts, speaking, and media so more people understand that plaque can be seen, measured, and driven into retreat

How he works with your care team

Because ClearCardio serves patients from across the country, Dr. Osborne can't meet individually with everyone. Instead, he works behind the scenes with our ClearCardio physicians, reviewing your imaging and labs, weighing in on complex cases, and shaping the strategy for your treatment plan.

You may never sit across a desk from him. But when your ClearCardio doctor walks in with a clear explanation of your plaque, a step-by-step plan, and a way to prove if it's working or not, you're seeing Dr. Osborne's life's work in action.

His goal isn't to put more stents in. He hasn't performed a diagnostic heart catheterization in over 20 years. His goal is to make sure you never need one.

Book a call

Stop guessing. Get real answers about your heart.

One visit in person. Ongoing prevention by telehealth.

Wherever you live, you can apply to join ClearCardio's patent-pending prevention program. You'll start with a single on-site visit at one of our clinics, then continue your care through structured telehealth visits, virtual coaching and remote monitoring designed to track and treat plaque over time.

With 30 years of preventative cardiology, 25,000 evaluations over 21 years and a proven process, you're in excellent hands. On your Patient Assessment Call we'll review your history and goals, explain how travel and telehealth would work for you, and make sure the program is a good fit before you commit.

  • Secure, HIPAA-compliant telehealth platform
  • No obligation — your first step is an assessment, not a contract
  • Evaluated by Dr. Osborne's specialized Patient Assessment Team

Book a Patient Assessment

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